Abstract

Endoscopy is an extremely valuable instrument to evaluate the effectiveness of new treatments for patients with ulcerative colitis; however it is necessary to validate the current endoscopic classifications to facilitate meaningful comparisons between them. The Ulcerative Colitis Endoscopic Index of Severity (UCEIS) recommended by European Crohns and Colitis Organisation uses 3 parameters (vascular, bleeding, and ulceration), each with 3-4 levels of severity. However, it has not been validated for the Mexican population. In addition to the colonoscopic features, the establishment of disease activity by histology is performed routinely. The Riley scale shows mainly the density and distribution of neutrophils in mucosal defects. To determine whether there is a correlation between the UCEIS endoscopic classification and the Riley histological classification, and validate their usefulness in the Mexican population. A retrospective, cross-sectional, open study was conducted from January 2012 to December 2014 in the Centro Medico Nacional 20 de Noviembre on patients with a diagnosis of ulcerative colitis sent to the hospital Endoscopy Department. Endoscopic UCEIS and histological Riley classifications were determined and compared using the SPSS program for statistical analysis. A total of 63 cases were included, of whom 33 were male (52%) and 30 (48%) female, with mean age of 50 years (23-78 years). The Spearman correlation coefficient was 89.8%, with a confidence interval of 83.7%-93.7% (P < .001). Using the Kendall coefficient, a correlation of 80.1% was observed between the variables with a confidence interval ranging from 70.5% to 86.4% (P < .0001. In accordance to the objective of the investigation, it was concluded that the correlation between the variables is significant, therefore the endoscopic and histological classifications used in ulcerative colitis correlate, and both are valid for use in the Mexican population.