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• Clinical and pathological results of denosumab treatment for giant cell tumors of bone: Prospective study of 14 cases

  M. Deveci, S. Paydaş, G. Gönlüşen, C. Özkan, Ö. Biçer, M. Tekin

  Collection of Acta Orthopaedica et Traumatologica Turcica (2017).

  
  

  Abstract

  Giant cell tumor of bone (GCT) is a primary, osteolytic, benign tumor of the bone. Surgery is the commonly used treatment, however, recurrence remains a problem. Receptor activator of nuclear factor kappa B (RANKL) is responsible for the formation of osteoclastic cells. Discovery of RANKL and its human monoclonal antibody, denosumab, led to use of denosumab for treatment of GCT. The aim of this study was to evaluate clinical and pathological results of treatment of GCT with denosumab and to assess adverse effect profile and recurrence rate. Thirteen patients with 14 lesions were enrolled in the study. Mean age was 38.3 years. Patients were given subcutaneous injections of denosumab (120 mg) every 4 weeks (with additional doses on days 0, 8 and 15 in cycle 1 only) and were radiologically evaluated for tumor response. Pain and functional status were measured using Visual Analog Score (VAS) and Musculoskeletal Tumor Society Score (MSTS). Adverse effects were analyzed after each cycle. Participants were 5 men and 8 women. Mean follow-up was 17 months. One lesion was Campanacci grade I, 8 were grade II, and 5 were grade III. Eight lesions were recurrent, and remaining were primary lesions. After average of 9 cycles (range: 4–17 cycles), all tumors underwent radiological regression. Ten lesions were removed surgically. More than 90% of giant cells were found to have regressed in all pathological specimens. On last follow-up, average VAS was 1 and MSTS was 87%. Fatigue and joint and muscle pain after injections was reported by 46% of patients, and mild hypocalcaemia was seen in 1 patient. Denosumab has been shown to be a successful drug in treatment of GCT. Denosumab can be used as neoadjuvant for all recurrent lesions, grade II lesions with high surgical risk, grade III lesions, and metastatic cases of GCT. Level IV, Therapeutic study

  Abstract
  Giant cell tumor of bone (GCT) is a primary, osteolytic, benign tumor of the bone. Surgery is the commonly used treatment, however, recurrence remains a problem. Receptor [...]

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• Efficacy of preoperative administration of single high dose intravenous tranexamic acid in reducing blood loss in total knee arthroplasty: A prospective clinical study

  T. Akgül, M. Büget, A. Salduz, İ. Edipoğlu, M. Ekinci, S. Küçükay, C. Şen

  Collection of Acta Orthopaedica et Traumatologica Turcica (2017).

  
  

  Abstract

  The aim of this study was to analyse the effectiveness of single dose of 20 mg/kg intravenous tranexamic acid (TXA), in reducing the blood loss in patients undergoing total knee arthroplasty (TKA). 70 patients (65.5 ± 8.1 years old) that have undergone TKA were divided in two groups. The 20 mg/kg IV TXA was given before the skin incision to one group (study group). On the control group, TKA was performed without TXA. The demographic data, body mass index, amount of bleeding and erythrocyte infusion during the operation, hemoglobin and hematocrit values (preoperative and 48th hour), the amount of drainage after the operation were compared between the groups. The total amount of bleeding in the study group was 634.03 ± 182.88 ml and 1166.42 ± 295.92 ml in the control group (p < 0.001). Perioperative bleeding was 252.01 ± 144.13 ml in the study group and 431.33 ± 209.10 ml in the control group (p = 0.018). The drainage after the operation was 311.11 ± 141.64 ml at the 24th hour in the study group, 640.74 ± 279.43 ml at the 24th hour in the control group (p < 0.001). The drainage after 24th hour was 97.96 ± 115.86 ml in the study group and 112.96 ± 64.43 ml in the control group (p = 0.584). A high, single dose of TXA intravenously given to the patient prior to the TKA significantly reduces the bleeding during the operation and within the postoperative 24 h. There is no significant change in the bleeding amount after the 24th hour following the operation.

  Abstract
  The aim of this study was to analyse the effectiveness of single dose of 20 mg/kg intravenous tranexamic acid (TXA), in reducing the blood loss in patients undergoing total [...]

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• Retraction notice to “A new femoral nail with single distal locking screw for maximum interfragment rotational stability” Acta Orthop Traumatol Turc 2016;50(1):89–96

  A. Karaarslan, H. Aycan, Y. Örgen, A. Karakaşli, F. Ertem, E. Sesli

  Collection of Acta Orthopaedica et Traumatologica Turcica (2017).

  
  

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• Short Form Health Survey version-2.0 Turkish (SF-36v2) is an efficient outcome parameter in musculoskeletal research

  C. García, D. Çelik, Ö. Çoban

  Collection of Acta Orthopaedica et Traumatologica Turcica (2017).

  
  

  Abstract

  Although the Short Form Health Survey version-2.0 (SF-36v2) is widely used since 2000, the researchers and clinicians in Turkey have been still using the original version. However, the original version includes many deficiencies and the SF-36v2 was introduced aiming to correct these deficiencies. The purpose of this study is to indicate differences between SF-36 and SF-36v2 and the present cross cultural adaptation, reliability and validity of the SF-36v2. The SF-36v2 was cross culturally adapted to Turkish and the measurement properties of the Turkish version of the SF-36v2 were tested in 50 patients (19 males, mean ± SD age: 36.9 ± 14.6 years, range: 16–65 years, BMI, 24.1 ± 4.6) with a variety of musculoskeletal pathologies. Intraclass correlation coefficients (ICC) were used to estimate the test-retest reliability. Construct validity was analyzed with SF-36v2 and EuroQol Group (EQ-5D). The distribution of ceiling and floor effects was determined. During the cross-cultural adaptation process many changes were made. The Turkish SF-36v2 subscales showed excellent test-retest reliability which was ranged 0.80 to 0.95. The highest correlation was found between SF-36v2-PCS and SF-36v2-PF (r = 0.75), the lowest correlation was found between SF-36v2-PCS and SF-36v2-MH (r = 0.05). The correlations between EQ-5D and SF-36v2 subscales ranged from 0.10 (SF-36v2 –VT) to 0.46 (SF-36v2 –RE). We observed no ceiling and floor effects. The cultural adaptation of the SF-36v2 was successful. The SF-36v2 has sufficient reliability and validity to measure a variety of musculoskeletal pathologies for Turkish-speaking individuals.

  Abstract
  Although the Short Form Health Survey version-2.0 (SF-36v2) is widely used since 2000, the researchers and clinicians in Turkey have been still using the original version. [...]

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• Usando Instrucción Programada por Computadora para el Entrenamiento de Diseños de Sistema Orientados a Metas

  N. Weatherly, A. International, R. Malott

  Collection of Acta de Investigación Psicológica (2017).

  
  

  Abstract

  The purpose of this study was to evaluate two versions of a programmed instruction training program designed to teach undergraduate college students a goal-directed systems approach to analyzing organizational systems (Malott & Garcia, 1987). The first version was a paper-based programmed instruction module that had previously been shown to be effective at training the basic knowledge of the concepts, however was ineffective at training the application of these concepts. A computer-based programmed instruction (CBPI) version was created to improve the application of these concepts, which was tested through a series of three open-ended posttests with increasingly explicit prompts for each successive test. The results of the study showed higher performance results for the CBPI versions across all three dependent variables. The results of a nonparametric global test showed a standardized effect size of .86 and a p-value of

  Abstract
  The purpose of this study was to evaluate two versions of a programmed instruction training program designed to teach undergraduate college students a goal-directed systems [...]

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• Inclusion and exclusion parameters in happiness and life satisfaction outliners in Mexico

  J. Noriega, F. Arellanes, H. Freire, I. Millán

  Collection of Acta de Investigación Psicológica (2017).

  
  

  Abstract

  The present analysis is made about the National Survey Well-being (BIARE, for its acronym in Spanish) constructed by National Institute of Statistics and Geography (INEGI) for obtain subjective indicators well-being and happiness. The objective its to know the characteristics and differences between the people who report the lowest well-being and the highest well-being perception. The happiness indicator was selected from the questions: «How satisfied are you? » and «How many happy are you?», which have a ten-point responding scale, happy people was selected from point 10 (totally satisfied). People unhappy was selected from point 0 = «Nothing satisfied» and point 1 = «A little satisfied». Descriptive statistics and hypothesis test was performed for evaluate group differences using chi-square and U Mann-Whitney test. The conclusion its that the unhappy people, compared with the happy people, perceive unhappiness during long time, obtained achievements and recognition were lowest for unhappy people, more presence of diseases, few economic resources, few social contact with family and friends, lower capacity to give support to people and a lower perception of coping capacities.

  Abstract
  The present analysis is made about the National Survey Well-being (BIARE, for its acronym in Spanish) constructed by National Institute of Statistics and Geography (INEGI) [...]

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• Exploratory analysis of the scale of Sternberg love in university Peruvian students

  J. León, T. Rodríguez

  Collection of Acta de Investigación Psicológica (2017).

  
  

  Abstract

  The article describes the properties psicométricas of the Triangular Scale of the Love of Sternberg (1986) (ETAS). The scale was administered to 455 university students of Metropolitan Lima, 145 males and 310 women, whose ages ranged between 16 to 51 years. The results reveal a reliability, by means of Cronbachs alfa, for the total scale of .964. The factors intimidate, commitment and passion present indexes of reliability of .947.922 and.848 respectively. All the coefficients of reliability are considered to be excellent. The analysis factorial exploratorio suggested that they are three factors those that sublie to the articles, though there is evidence of the existence of an alone factor. One concludes that the ETAS presents suitable properties psicométrica, an analysis being recommended to realize factorial confirmatory in order to check the internal structure.

  Abstract
  The article describes the properties psicométricas of the Triangular Scale of the Love of Sternberg (1986) (ETAS). The scale was administered to 455 university students of [...]

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• Evaluation of a Treatment Program to Stop Drinking

  M. Altamirano, A. Alcaráz, L. García, M. Cáceres

  Collection of Acta de Investigación Psicológica (2017).

  
  

  Abstract

  The aim of the study was to evaluate the results of the treatment program for people who have problems with their drinking developed at Centros de Integración Juvenil, institute dedicated to treat, prevent and investigate addictions in Mexico. The evaluation was made by a cuanticualitative, transversal, comparative, ex post facto design. The first estimate was carried out with a purposive sample of 170 people (133 men and 37 women) who were participating in the treatment program. To do this, was design the test of Program Evaluation for Drinkers (CEPROBE ) to examine the emotional and health state, social integration, criminal behavior, assertiveness to confront the offer of alcohol, habit changes attributed to alcohol program and to assess service quality standards. For the second analysis, 24 Psychologists and 1 Physician (18 men and 7 women) were interviewed it means at an open questionnaire that explores the experience of the therapist in the course of the program. Overall, 47.3% of the patients decreased de use of alcohol, while 48.5% were able to quit it. With the Kruskal-Wallis test, the results suggest significant differences in the socio-emotional status mentioned and alcohol use of the subjects. Under the perception of patients and therapist, the program fulfilled adequately quality standards.

  Abstract
  The aim of the study was to evaluate the results of the treatment program for people who have problems with their drinking developed at Centros de Integración Juvenil, institute [...]

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• Construct and Psychometric Validation of the Dwelling’s Privacy Scale

  E. Velasco, S. Mercado, I. Lagunes

  Collection of Acta de Investigación Psicológica (2017).

  
  

  Abstract

  The main objective of this research was to generate a reliable and valid scale that assessed dwelling privacy in Mexico City’s population. A scale was developed specifically for this purpose. The scale included 20 items with five options for answers (Never, few times, sometimes, frequently and always). The scale was applied to a sample of 200 Mexico City’s inhabitants in order to obtain its psychometrical validation. The distribution of the participants was as follow: age between 14 to 75, 110 women and 90 men: diverse occupations and school levels. A proper analysis took place in order to learn about the items discriminative power, reliability and valid factorial structure. The final scale was conformed by 11 items organized by three factors as follow: 1) Information Access Control, 2) Person Access Control and 3) Intimacy it explains 68% of variance and has a reliability of Cronbach Alpha =0.89. Afterwards a Confirmatory Factor Analysis was conducted to verify if the structure obtained from the Principal Component Analysis was correct, and a good fit was achieved (df=39, x2= 48.07, p = .151, CFI= .987, RMSEA= .032).

  Abstract
  The main objective of this research was to generate a reliable and valid scale that assessed dwelling privacy in Mexico City’s population. A scale was developed specifically [...]

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• Redefiniendo la felicidad: frecuencia versus intensidad

  P. Matus, G. Orozco, S. Aragón, R. Loving

  Collection of Acta de Investigación Psicológica (2017).

  
  

  Abstract

  Mexico is consistently portrayed as a happy country. Research endeavors, both national and international, show that Mexicos levels of happiness are favorable, although little has been done regarding specific measurement underpinnings. There is a constant debate on whether happiness should be measured in terms of frequency or intensity of positive affect over negative affect (Diener, Sandvik, & Pavot, 2009), although some consensus points toward frequencys superiority over intensity of emotions. Some authors insist that frequency can me more easily and accurately measured than intensity, allowing for cross-person metric comparisons. This research put to test the frequency-intensity debate by providing several conceptual frameworsk that accentuated one over the other, allowing people to decide how they defined their own happiness. Two independent samples (n1 = 158, n2 = 583) of Mexican men and women provided insights on whether happiness in Mexico is defined in terms of frequency or intensity. Once it was defined, happiness levels were compared between two groups showing that those who define happiness as “frequency” present higher levels of joy. This research supports the premise that happiness could be defined as the sum of frequent events, congruent with bottom-up approaches to happiness and wellbeing.

  Abstract
  Mexico is consistently portrayed as a happy country. Research endeavors, both national and international, show that Mexicos levels of happiness are favorable, although little [...]

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